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Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19
(Life Science Alliance, 2022-01-10)
Plitidepsin, a marine-derived cyclic-peptide, inhibits SARS-CoV-2 replication at nanomolar concentrations by targeting the host protein eukaryotic translation elongation factor 1A. Here, we show that ...
Kinetics of immune responses elicited after three mRNA COVID-19 vaccine doses in predominantly antibody-deficient individuals
(Cell Press, 2022-10-28)
Mass vaccination campaigns reduced COVID-19 incidence and severity. Here, we evaluated the immune responses developed in SARS-CoV-2-uninfected patients with predominantly antibody-deficiencies (PAD) ...
Ostreopsis cf. ovata and Ostreopsis lenticularis (Dinophyceae: Gonyaulacales) in the Galapagos Marine Reserve
(Consejo Superior de Investigaciones Científicas, 2020-06-15)
The genus of benthic dinoflagellates Ostreopsis is of particular interest because some species negatively impact human health and coastal marine ecosystems. Ostreopsis populations from a remote area, ...
Adaptation of the European Fish Index (EFI+) to Include the Alien Fish Pressure
(MDPI, 2023-12-29)
The European Fish Index EFI+ is the only fish-based multimetric index for the assessment of the ecological status of running waters that is validated and thus applicable across most countries of the ...
Whole genome sequencing and de novo assembly of Staphylococcus pseudintermedius: a pangenome approach to unravelling pathogenesis of canine pyoderma
(Wiley, 2021-11-18)
Background
Staphylococcus pseudintermedius is the main aetiological agent of canine pyoderma. Whole genome sequencing is the most comprehensive way of obtaining relevant genomic information about ...
Welfare of pigs during transport
(Wiley Open Access, 2022-09-07)
In the framework of its Farm to Fork Strategy, the Commission is undertaking a comprehensive evaluation of the animal welfare legislation. The present Opinion deals with protection of pigs during ...
Chronological brain lesions after SARS-CoV-2 infection in hACE2-transgenic mice
(SAGE Publications, 2021-12-27)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes respiratory disease, but it can also affect other organs including the central nervous system. Several animal models have been developed ...
Frequency of Detection and Phylogenetic Analysis of Porcine circovirus 3 (PCV-3) in Healthy Primiparous and Multiparous Sows and Their Mummified Fetuses and Stillborn
(MDPI, 2020-07-02)
Porcine circovirus 3 (PCV-3) has been suggested as a putative causal agent of swine reproductive disease. A number of different studies have pointed out this association, but there is still a lack of ...
The Role of Birds of Prey in West Nile Virus Epidemiology
(MDPI, 2020-09-21)
Reported human cases of West Nile virus (WNV) in Europe increased dramatically in
2018. Lineage 1 strains had been circulating in Euro-Mediterranean countries since the early 1990s.
The subsequent ...
The effects of colostrum consumption and feed restriction during marketing and transportation of male dairy beef calves: Impact on pre-transport nutritional status and on farm recovery
(Elsevier, 2023-08-23)
The aim of this study was to evaluate the effects of colostrum consumption and feed restriction on biomarkers of stress, nutritional and health status, gut functionality, and behavior in male dairy beef ...