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Integration of liver gene co-expression networks and eGWAs analyses highlighted candidate regulators implicated in lipid metabolism in pigs
(Nature Research, 2017-04-19)
In the present study, liver co-expression networks and expression Genome Wide Association Study
(eGWAS) were performed to identify DNA variants and molecular pathways implicated in the functional
regulatory ...
Conserved Synthetic Peptides from the Hemagglutinin of Influenza Viruses Induce Broad Humoral and T-Cell Responses in a Pig Model
(Public Library of Science, 2012-07-16)
Outbreaks involving either H5N1 or H1N1 influenza viruses (IV) have recently become an increasing threat to cause potential
pandemics. Pigs have an important role in this aspect. As reflected in the ...
Liver transcriptome profile in pigs with extreme phenotypes of intramuscular fatty acid composition
(BMC, 2012-10-11)
Background: New advances in high-throughput technologies have allowed for the massive analysis of genomic
data, providing new opportunities for the characterization of the transcriptome architectures. ...
Machine learning applied to transcriptomic data to identify genes associated with feed efficiency in pigs
(BMC, 2019-03-13)
Background: To date, the molecular mechanisms that underlie residual feed intake (RFI) in pigs are unknown. Results
from diferent genome‑wide association studies and gene expression analyses are not ...
Polymorphism in the ELOVL6 Gene Is Associated with a Major QTL Effect on Fatty Acid Composition in Pigs
(Public Library of Science, 2013-01-14)
Background: The ELOVL fatty acid elongase 6 (ELOVL6), the only elongase related to de novo lipogenesis, catalyzes the ratelimiting step in the elongation cycle by controlling the fatty acid balance in ...
VtaA8 and VtaA9 from Haemophilus parasuis delay phagocytosis by alveolar macrophages
(BMC, 2012-07-27)
Haemophilus parasuis, a member of the family Pasteurellaceae, is a common inhabitant of the upper respiratory tract
of healthy pigs and the etiological agent of Glässer’s disease. As other virulent ...
Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat
(Nature Research, 2016-08-18)
The aim of this work is to better understand the genetic mechanisms determining two complex traits
affecting porcine meat quality: intramuscular fat (IMF) content and its fatty acid (FA) composition. ...
Identification of strong candidate genes for backfat and intramuscular fatty acid composition in three crosses based on the Iberian pig
(Nature Research, 2020-08-18)
Meat quality has an important genetic component and can be modified by the fatty acid (FA) composition and the amount of fat contained in adipose tissue and muscle. The present study aimed to find genomic ...
A gene co-association network regulating gut microbial communities in a Duroc pig population
(BMC, 2021-02-21)
Background. Analyses of gut microbiome composition in livestock species have shown its potential to contribute to the regulation of complex phenotypes. However, little is known about the host genetic ...
Multi‑breed and multi‑trait co‑association analysis of meat tenderness and other meat quality traits in three French beef cattle breeds
(BMC, 2016-04-23)
Background: Studies to identify markers associated with beef tenderness have focused on Warner–Bratzler shear force (WBSF) but the interplay between the genes associated with WBSF has not been explored. ...