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Co-expression network analysis predicts a key role of microRNAs in the adaptation of the porcine skeletal muscle to nutrient supply
(BMC, 2020-01-17)
Background
The role of non-coding RNAs in the porcine muscle metabolism is poorly understood, with few studies investigating their expression patterns in response to nutrient supply. Therefore, we aimed ...
Analysing the Expression of Eight Clock Genes in Five Tissues From Fasting and Fed Sows
(Frontiers Media, 2018-10-18)
In a previous study, we observed that circadian clock genes are differentially expressed
in the skeletal muscle of fasting and fed sows. The goal of the current work was
to investigate if these genes ...
Dietary intake of bioactive ingredients impacts liver and adipose tissue transcriptomes in a porcine model of prepubertal early obesity
(Nature Research, 2020-03-25)
Global prevalence of obesity has increased to epidemic proportions over the past 40 years, with childhood obesity reaching alarming rates. In this study, we determined changes in liver and adipose tissue ...
Polymorphisms of the cryptochrome 2 and mitoguardin 2 genes are associated with the variation of lipid-related traits in Duroc pigs
(Nature Research, 2019-06-21)
The genetic factors determining the phenotypic variation of porcine fatness phenotypes are still largely
unknown. We investigated whether the polymorphism of eight genes (MIGA2, CRY2, NPAS2, CIART,
ARNTL2, ...
Comparing the mRNA expression profile and the genetic determinism of intramuscular fat traits in the porcine gluteus medius and longissimus dorsi muscles
(BMC, 2019-03-04)
Background
Intramuscular fat (IMF) content and composition have a strong impact on the nutritional and organoleptic properties of porcine meat. The goal of the current work was to compare the patterns ...
Gut eukaryotic communities in pigs: diversity, composition and host genetics contribution
(BMC, 2020-05-07)
Background
The pig gut microbiome harbors thousands of species of archaea, bacteria, viruses and eukaryotes such as protists and fungi. However, since the majority of published studies have been focused ...
Leveraging host-genetics and gut microbiota to determine immunocompetence in pigs
(BMC, 2021-10-24)
Background: The gut microbiota infuences host performance playing a relevant role in homeostasis and function of
the immune system. The aim of the present work was to identify microbial signatures ...
Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources
(Nature Research, 2021-02-09)
Coronaviruses silently circulate in human and animal populations, causing mild to severe diseases. Therefore, livestock are important components of a “One Health” perspective aimed to control these viral ...
kernInt: A Kernel Framework for Integrating Supervised and Unsupervised Analyses in Spatio-Temporal Metagenomic Datasets
(Frontiers Media, 2021-01-28)
The advent of next-generation sequencing technologies allowed relative quantification of microbiome communities and their spatial and temporal variation. In recent years, supervised learning (i.e., ...
Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes
(BMC, 2021-05-04)
Background: Mature microRNAs (miRNAs) play an important role in repressing the expression of a wide range of
mRNAs. The presence of polymorphic sites in miRNA genes and their corresponding 3′UTR binding ...