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Gut barrier-microbiota imbalances in early life lead to higher sensitivity to inflammation in a murine model of C-section delivery
(BMC, 2023-07-03)
Background Most interactions between the host and its microbiota occur at the gut barrier, and primary colonizers
are essential in the gut barrier maturation in the early life. The mother–ofspring ...
High-Fat Diet-Induced Obesity Increases Brain Mitochondrial Complex I and Lipoxidation-Derived Protein Damage
(MDPI, 2024-01-26)
Obesity is a risk factor for highly prevalent age-related neurodegenerative diseases, the pathogenesis of whichinvolves mitochondrial dysfunction and protein oxidative damage. Lipoxidation, driven by ...
Safety and Efficacy upon Infection in Sheep with Rift Valley Fever Virus ZH548-rA2, a Triple Mutant Rescued Virus
(MDPI, 2024-01-05)
The introduction of three single nucleotide mutations into the genome of the virulent RVFV
ZH548 strain allows for the rescue of a fully attenuated virus in mice (ZH548-rA2). These mutations
are located ...
Optimising sewage sludge anaerobic digestion for resource recovery in wastewater treatment plants
(Elsevier, 2024-02-08)
Recovering resources from sludge generated during wastewater treatment is both an opportunity and a challenge. Thermophilic anaerobic digestion may optimise biogas production and digested sludge properties ...
Copy Number Variation on ABCC2-DNMBP Loci Affects the Diversity and Composition of the Fecal Microbiota in Pigs
(American Society for Microbiology, 2023-05-31)
Genetic variation in the pig genome partially modulates the composition of porcine gut microbial communities. Previous studies have been focused on the association between single nucleotide polymorphisms ...
MicroRNA expression in specific segments of the pig periovulatory internal genital tract is differentially regulated by semen or by seminal plasma
(Elsevier, 2024-01-02)
microRNAs play pivotal roles during mammalian reproduction, including the cross-talk between gametes, embryos and the maternal genital tract. Mating induces changes in the expression of mRNA transcripts ...
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation
(Springer Nature, 2023-12-18)
Acute infection and chronic infection are the two most common fates of pathogenic virus infections. While several factors that
contribute to these fates are described, the critical control points and ...
A Protein Misfolding Shaking Amplificationbased method for the spontaneous generation of hundreds of bona fide prions
(Nature Research, 2024-03-08)
Prion diseases are a group of rapidly progressing neurodegenerative disorders
caused by the misfolding of the endogenous prion protein (PrPC) into a
pathogenic form (PrPSc). This process, despite being ...
Retos y oportunidades para la evaluación del estado ecológico en ríos temporales
(Asociación Española de Ecología Terrestre, 2024-03-06)
Los ríos temporales (RTs) son ecosistemas fluviales en los que los efectos de las perturbaciones antrópicas se mezclan con los de la propia perturbación natural que impone la temporalidad del flujo. A ...
Integrating spatiotemporal hydrological connectivity into conservation planning to protect temporary rivers
(Wiley, 2024-03-25)
1. Temporary rivers (TRs) have been largely overlooked in conservation assessments. Because TRs are such dynamic ecosystems, spatial and temporal aspects of their hydrology and ecology need to be taken ...