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Coinfection with Entamoeba polecki and Brachyspira hyodysenteriae in a pig with severe diarrhea
(SAGE Publications, 2019-02-09)
Enteric disease in pigs is usually of multifactorial etiology, including infectious and non-infectious factors. In many cases of endemic diarrhea in weaner-to-finisher pigs, the combination of 2 or more ...
Monkeypox (Mpox) requires continued surveillance, vaccines, therapeutics and mitigating strategies
(Elsevier, 2023-04-21)
The widespread outbreak of the monkeypox virus (MPXV) recognized in 2022 poses new challenges for public healthcare systems worldwide. With more than 86,000 people infected, there is concern that MPXV ...
Unraveling the antiviral activity of plitidepsin against SARS-CoV-2 by subcellular and morphological analysis
(Elsevier, 2022-02-26)
The pandemic caused by the new coronavirus SARS-CoV-2 has made evident the need for broad-spectrum, efficient antiviral treatments to combat emerging and re-emerging viruses. Plitidepsin is an antitumor ...
Gut‑associated microbes are present and active in the pig nasal cavity
(Nature Research, 2024-04-11)
The nasal microbiota is a key contributor to animal health, and characterizing the nasal microbiota
composition is an important step towards elucidating the role of its diferent members. Eforts ...
Enhanced antiviral immunity and dampened inflammation in llama lymph nodes upon MERS-CoV sensing: bridging innate and adaptive cellular immune responses in camelid reservoirs
(Frontiers Media, 2023-06-14)
Middle East respiratory syndrome coronavirus (MERS-CoV) infection can cause fatal pulmonary inflammatory disease in humans. Contrarily, camelids and bats are the main reservoir hosts, tolerant for ...
Pigs are not susceptible to SARS‐CoV‐2 infection but are a model for viral immunogenicity studies
(Wiley, 2020-10-02)
Conventional piglets were inoculated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) through different routes, including intranasal, intratracheal, intramuscular and intravenous ones. ...
Immunisation efficacy of a stabilised SARS-CoV-2 spike glycoprotein in two geriatric animal models
(Nature Research, 2024-02-27)
AgeisassociatedwithreducedefficacyofvaccinesandlinkedtohigherriskofsevereCOVID-19.Herewe
determined the impact of ageing on the efficacy of a SARS-CoV-2 vaccine based on a stabilised Spike
glycoprotein ...
Diagnosis by ruling out other diseases or conditions
(BMJ Publishing Group, 2018-07-19)
Pig production is nowadays highly specialised, and is dominated by large, intensive, indoor-rearing production systems around the world. As farming systems have evolved, so also has our understanding ...
Increasing breast milk betaine modulates Akkermansia abundance in mammalian neonates and improves long-term metabolic health
(American Association for the Advancement of Science, 2021-03-31)
Accelerated postnatal growth is a potentially modifiable risk factor for future obesity. To study how specific breast milk components contribute to early growth and obesity risk, we quantified one-carbon ...
Frequency of PCV-2 viremia in nursery piglets from a Spanish swine integration system in 2020 and 2022 considering PRRSV infection status
(BMC, 2024-01-16)
Background Porcine circovirus 2 (PCV‑2) poses a signifcant economic threat for the swine industry, causing a range
of diseases collectively referred to as porcine circovirus diseases (PCVDs). Despite ...