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On the holobiont ‘predictome’ of immunocompetence in pigs
(BMC, 2023-05-01)
Background
Gut microbial composition plays an important role in numerous traits, including immune response. Integration of host genomic information with microbiome data is a natural step in the prediction ...
Functional and association studies on the pig HMGCR gene, a cholesterol-synthesis limiting enzyme
(Cambridge University Press, 2009-10-23)
The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) is the rate-limiting enzyme in the biosynthesis of cholesterol. We have
studied the role of the HMGCR gene in pig lipid metabolism by means of ...
Efect of feed restriction on the environmental variability of birth weight in divergently selected lines of mice
(BMC, 2019-06-13)
Selection of mice for decreased environmental variability of birth weight has achieved higher survivability and larger litter size as a correlated response to canalized selection, which suggests higher ...
Social network analysis of agonistic behaviour and its association with economically important traits in pigs
(MDPI, 2020-11-16)
Aggression behaviour has several negative consequences on the performance and welfare of pigs. Here, the Social Network Analysis (SNA) approach was employed to (1) identify individual traits that describe ...
Impact of multi-output and stacking methods on feed efficiency prediction from genotype using machine learning algorithms
(Wiley, 2023-07-05)
Feeding represents the largest economic cost in meat production; therefore, selection to improve traits related to feed efficiency is a goal in most livestock breeding programs. Residual feed intake ...
Mutations on a conserved distal enhancer in the porcine C-reactive protein gene impair its expression in liver
(Frontiers Media, 2023-09-14)
C-reactive protein (CRP) is an evolutionary highly conserved protein. Like humans, CRP acts as a major acute phase protein in pigs. While CRP regulatory mechanisms have been extensively studied in humans, ...
Gut eukaryotic communities in pigs: diversity, composition and host genetics contribution
(BMC, 2020-05-07)
Background
The pig gut microbiome harbors thousands of species of archaea, bacteria, viruses and eukaryotes such as protists and fungi. However, since the majority of published studies have been focused ...
Role of AMPK signalling pathway during compensatory growth in pigs
(BioMed Central, 2018-09-17)
Background: The molecular basis of compensatory growth in monogastric animals has not yet been fully explored.
Herewith, in this study we aim to determine changes in the pig skeletal muscle transcriptome ...
Segregation of Regulatory Polymorphisms with Effects on the Gluteus Medius Transcriptome in a Purebred Pig Population
(Public Library of Science, 2012-04-24)
Background: The main goal of the present study was to analyse the genetic architecture of mRNA expression in muscle, a
tissue with an outmost economic importance for pig breeders. Previous studies have ...
Selection of Internal Control Genes for Real-Time Quantitative PCR in Ovary and Uterus of Sows across Pregnancy
(Public Library of Science, 2013-06-13)
Background: Reproductive traits play a key role in pig production in order to reduce costs and increase economic returns. Among others, gene expression analyses represent a useful approach to study ...