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Unraveling the antiviral activity of plitidepsin against SARS-CoV-2 by subcellular and morphological analysis
(Elsevier, 2022-02-26)
The pandemic caused by the new coronavirus SARS-CoV-2 has made evident the need for broad-spectrum, efficient antiviral treatments to combat emerging and re-emerging viruses. Plitidepsin is an antitumor ...
2023 International African Swine Fever Workshop: Critical Issues That Need to Be Addressed for ASF Control
(MDPI, 2023-12-19)
The 2023 International African Swine Fever Workshop (IASFW) took place in Beijing,
China, on 18–20 September 2023. It was jointly organized by the U.S.-China Center for Animal
Health (USCCAH) at Kansas ...
Identification of Promiscuous African Swine Fever Virus T-Cell Determinants Using a Multiple Technical Approach
(MDPI, 2021-01-07)
The development of subunit vaccines against African swine fever (ASF) is mainly hindered by the lack of knowledge regarding the specific ASF virus (ASFV) antigens involved in protection. As a good ...
First Report of Streptococcus ruminantium in Wildlife: Phenotypic Differences with a Spanish Domestic Ruminant Isolate
(MDPI, 2022-02-08)
Streptococcus ruminantium is a recent reclassification of the former Streptococcus suis serovar 33. Although knowledge about S. suis is extensive, information on S. ruminantium host range and pathogenic ...
Intensive antibiotic treatment of sows with parenteral crystalline ceftiofur and tulathromycin alters the composition of the nasal microbiota of their ofspring
(BMC, 2023-11-24)
The nasal microbiota plays an important role in animal health and the use of antibiotics is a major factor that infu‑
ences its composition. Here, we studied the consequences of an intensive antibiotic ...
A global analysis of CNVs in swine using whole genome sequence data and association analysis with fatty acid composition and growth traits
(Public Library of Science, 2017-05-04)
Copy number variations (CNVs) are important genetic variants complementary to SNPs, and can be considered as biomarkers for some economically important traits in domestic animals. In the present study, ...
Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2
(Cell Press, 2023-02-02)
Current COVID-19 vaccines have been associated with a decline in infection rates,
prevention of severe disease, and a decrease in mortality rates. However, SARSCoV-2 variants are continuously evolving, ...
Ceftiofur treatment of sows results in long‑term alterations in the nasal microbiota of the ofspring that can be ameliorated by inoculation of nasal colonizers
(BMC, 2023-10-20)
Background The nasal microbiota of the piglet is a reservoir for opportunistic pathogens that can cause polyse‑
rositis, such as Glaesserella parasuis, Mycoplasma hyorhinis or Streptococcus suis. ...
Characterization of porcine dendritic cell response to Streptococcus suis
(BMC, 2011-06-02)
Streptococcus suis is a major swine pathogen and important zoonotic agent causing mainly septicemia and
meningitis. However, the mechanisms involved in host innate and adaptive immune responses toward ...
Development of an antigen Enzyme-Linked AptaSorbent Assay (ELASA) for the detection of swine influenza virus in field samples
(Elsevier, 2021-08-09)
Influenza viruses are highly variable pathogens that infect a wide range of mammalian and avian species. According to the internal conserved proteins (nucleoprotein: NP, and matrix proteins: M), these ...