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Exploratory metagenomic analyses of periweaning failure-to-thrive syndrome-affected pigs
(BMJ Publishing Group, 2018-11-09)
Modern pig farming is characterised by the emergence of several syndromes whose aetiology is unclear or has a multifactorial origin, including periweaning failure-to-thrive syndrome (PFTS). In fact, its ...
Porcine circovirus type 3: a threat to the pig industry?
(BMJ Publishing Group, 2018-01-19)
The recent discovery of porcine circovirus 3 (PCV3) has caused some concern among field veterinarians and brought the attention of the scientific world, likely because of some similarities with porcine ...
Identification and Characterization of Swine Influenza Virus H1N1 Variants Generated in Vaccinated and Nonvaccinated, Challenged Pigs
(MDPI, 2021-10-16)
Influenza viruses represent a continuous threat to both animal and human health. The 2009 H1N1 A influenza pandemic highlighted the importance of a swine host in the adaptation of influenza viruses to ...
The economic impact of endemic respiratory disease in pigs and related interventions - a systematic review
(BMC, 2023-10-17)
Background Understanding the financial consequences of endemically prevalent pathogens within the porcine
respiratory disease complex (PRDC) and the effects of interventions assists decision-making ...
Animal models to study the neurological manifestations of the post-COVID-19 condition
(Nature Research, 2023-08-24)
More than 40% of individuals infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have experienced
persistent or relapsing multi-systemic symptoms months after the onset of coronavirus ...
A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity
(Nature Research, 2024-02-05)
Here we report the characterization of 17T2, a SARS-CoV-2 pan-neutralizing
human monoclonal antibody isolated from a COVID-19 convalescent individual infected during the first pandemic wave. 17T2 is a ...
Middle East respiratory coronavirus (MERS-CoV) internalized by llama alveolar macrophages does not result in virus replication or induction of pro-inflammatory cytokines
(Elsevier, 2024-03)
Severe Middle East respiratory syndrome (MERS) is characterized by massive infiltration of immune cells
in lungs. MERS-coronavirus (MERS-CoV) replicates in vitro in human macrophages, inducing high ...
Immunisation efficacy of a stabilised SARS-CoV-2 spike glycoprotein in two geriatric animal models
(Nature Research, 2024-02-27)
AgeisassociatedwithreducedefficacyofvaccinesandlinkedtohigherriskofsevereCOVID-19.Herewe
determined the impact of ageing on the efficacy of a SARS-CoV-2 vaccine based on a stabilised Spike
glycoprotein ...
Immunization with V987H-stabilized Spike glycoprotein protects K18-hACE2 mice and golden Syrian hamsters upon SARS-CoV-2 infection
(Nature Research, 2024-03-21)
Safe and effective severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) vaccines are crucial to fight against the coronavirus disease 2019
pandemic. Most vaccines are based on a mutated version ...
Characterization of homologous and heterologous adaptive immune responses in porcine reproductive and respiratory syndrome virus infection
(BMC, 2012-04-19)
The present study characterized the homologous and heterologous immune response in type-I porcine
reproductive and respiratory syndrome virus (PRRSV) infection. Two experiments were conducted: in ...