Buscar
Mostrando ítems 281-290 de 295
Middle East respiratory coronavirus (MERS-CoV) internalized by llama alveolar macrophages does not result in virus replication or induction of pro-inflammatory cytokines
(Elsevier, 2024-03)
Severe Middle East respiratory syndrome (MERS) is characterized by massive infiltration of immune cells
in lungs. MERS-coronavirus (MERS-CoV) replicates in vitro in human macrophages, inducing high ...
A Protein Misfolding Shaking Amplificationbased method for the spontaneous generation of hundreds of bona fide prions
(Nature Research, 2024-03-08)
Prion diseases are a group of rapidly progressing neurodegenerative disorders
caused by the misfolding of the endogenous prion protein (PrPC) into a
pathogenic form (PrPSc). This process, despite being ...
Immunisation efficacy of a stabilised SARS-CoV-2 spike glycoprotein in two geriatric animal models
(Nature Research, 2024-02-27)
AgeisassociatedwithreducedefficacyofvaccinesandlinkedtohigherriskofsevereCOVID-19.Herewe
determined the impact of ageing on the efficacy of a SARS-CoV-2 vaccine based on a stabilised Spike
glycoprotein ...
Immunization with V987H-stabilized Spike glycoprotein protects K18-hACE2 mice and golden Syrian hamsters upon SARS-CoV-2 infection
(Nature Research, 2024-03-21)
Safe and effective severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) vaccines are crucial to fight against the coronavirus disease 2019
pandemic. Most vaccines are based on a mutated version ...
Field evaluation of an automated mosquito surveillance system which classifies Aedes and Culex mosquitoes by genus and sex
(BMC, 2024-03-01)
Background Mosquito‑borne diseases are a major concern for public and veterinary health authorities, highlighting
the importance of efective vector surveillance and control programs. Traditional ...
Development of a new loop-mediated isothermal amplification test for the sensitive, rapid, and economic detection of different genotypes of Classical swine fever virus
(Frontiers Media, 2024-04-15)
Background: Classical swine fever virus (CSFV) remains one of the most
important pathogens in animal health. Pathogen detection relies on viral RNA
extraction followed by RT-qPCR. Novel technologies ...
Leishmania Infection in Wild Lagomorphs and Domestic Dogs in North-East Spain
(MDPI, 2024-04-02)
Leishmania infantum is a zoonotic protozoan parasite distributed worldwide that is transmitted
by phlebotomine sandflies. Dogs are the main reservoir for human infections. However, in recent years,
the ...
Toxoplasma gondii in a Remote Subsistence Hunting-Based Indigenous Community of the Peruvian Amazon
(MDPI, 2024-04-26)
Toxoplasma gondii is a ubiquitous zoonotic protozoan parasite that infects a wide variety
range of warm-blooded animals. This study describes the epidemiological scenario of T. gondii in
an indigenous ...
Nanoparticle-Based Secretory Granules Induce a Specific and Long-Lasting Immune Response through Prolonged Antigen Release
(MDPI, 2024-02-27)
Developing prolonged antigen delivery systems that mimic long-term exposure to pathogens
appears as a promising but still poorly explored approach to reach durable immunities. In this study,
we have ...
Gut microbiome and resistome characterization of pigs treated with commonly used post-weaning diarrhea treatments
(BMC, 2024-05-03)
Background The global burden of antimicrobial resistance demands additional measures to ensure the sustainable
and conscious use of antimicrobials. For the swine industry, the post-weaning period is ...