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Expression analysis of porcine miR-33a/b in liver, adipose tissue and muscle and its potential role in fatty acid metabolism
(Public Library of Science, 2021-01-26)
mir-33a and mir-33b are co-transcribed with the SREBF2 and SREBF1 transcription factors, respectively. The main role of SREBF1 is the regulation of genes involved in fatty acid metabolism, while SREBF2 ...
Liver transcriptome profile in pigs with extreme phenotypes of intramuscular fatty acid composition
(BMC, 2012-10-11)
Background: New advances in high-throughput technologies have allowed for the massive analysis of genomic
data, providing new opportunities for the characterization of the transcriptome architectures. ...
Genome-wide linkage analysis of QTL for growth and body composition employing the PorcineSNP60 BeadChip
(BMC, 2012-05-20)
Background: The traditional strategy to map QTL is to use linkage analysis employing a limited number of markers.
These analyses report wide QTL confidence intervals, making very difficult to identify ...
Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat
(Nature Research, 2016-08-18)
The aim of this work is to better understand the genetic mechanisms determining two complex traits
affecting porcine meat quality: intramuscular fat (IMF) content and its fatty acid (FA) composition. ...
Integration of liver gene co-expression networks and eGWAs analyses highlighted candidate regulators implicated in lipid metabolism in pigs
(Nature Research, 2017-04-19)
In the present study, liver co-expression networks and expression Genome Wide Association Study
(eGWAS) were performed to identify DNA variants and molecular pathways implicated in the functional
regulatory ...
Analysis of porcine MUC4 gene as a candidate gene for prolificacy QTL on SSC13 in an Iberian × Meishan F2 population
(BMC, 2011-10-31)
Background: Reproductive traits, such as prolificacy, are of great interest to the pig industry. Better understanding
of their genetic architecture should help to increase the efficiency of pig ...
Interrelation between gut microbiota, SCFA, and fatty acid composition in pigs
(American Society for Microbiology, 2023-12-14)
The gut microbiota is a key player in the host metabolism. Some bacteria are able to ferment non-digestible compounds and produce short-chain fatty acids that the host can later transform and accumulate ...
Association between the pig genome and its gut microbiota composition
(Nature Research, 2019-06-19)
The gut microbiota has been evolving with its host along the time creating a symbiotic relationship. In this study, we assess the role of the host genome in the modulation of the microbiota composition ...
Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes
(BMC, 2021-05-04)
Background: Mature microRNAs (miRNAs) play an important role in repressing the expression of a wide range of
mRNAs. The presence of polymorphic sites in miRNA genes and their corresponding 3′UTR binding ...
Identification of strong candidate genes for backfat and intramuscular fatty acid composition in three crosses based on the Iberian pig
(Nature Research, 2020-08-18)
Meat quality has an important genetic component and can be modified by the fatty acid (FA) composition and the amount of fat contained in adipose tissue and muscle. The present study aimed to find genomic ...