Search
Now showing items 101-110 of 111
A shift in Porcine circovirus 3 (PCV‐3) history paradigm: Phylodynamic analyses reveal an ancient origin and prolonged undetected circulation in the worldwide swine population
(Wiley Open Access, 2019-09-30)
The identification of a new circovirus (Porcine circovirus 3, PCV-3) has raised a remarkable concern because of some analogies with Porcine circovirus 2 (PCV-2). Preliminary results suggest an extremely ...
Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant
(Frontiers Media, 2023-12-04)
Most COVID-19 vaccines are based on the SARS-CoV-2 Spike glycoprotein (S) or
their subunits. However, S shows some structural instability that limits its
immunogenicity and production, hampering the ...
Evaluation of alpaca tracheal explants as an ex vivo model for the study of Middle East respiratory syndrome coronavirus (MERS-CoV) infection
(BMC, 2022-09-02)
Middle East respiratory syndrome coronavirus (MERS-CoV) poses a serious threat to public health. Here, we established an ex vivo alpaca tracheal explant (ATE) model using an air-liquid interface culture ...
Identification and Characterization of Swine Influenza Virus H1N1 Variants Generated in Vaccinated and Nonvaccinated, Challenged Pigs
(MDPI, 2021-10-16)
Influenza viruses represent a continuous threat to both animal and human health. The 2009 H1N1 A influenza pandemic highlighted the importance of a swine host in the adaptation of influenza viruses to ...
Protection against reinfection with D614- or G614-SARS-CoV-2 isolates in golden Syrian hamster
(Taylor & Francis Open Access, 2021-04-29)
Reinfections with SARS-CoV-2 have already been documented in humans, although its real incidence is currently unknown. Besides having a great impact on public health, this phenomenon raises the question ...
Exploratory field study on the effects of porcine circovirus 2 (PCV-2) sow vaccination at different physiological stages mimicking blanket vaccination
(BMC, 2021-04-26)
Background: The objective of the present study was to explore the benefits of Porcine circovirus 2 (PCV-2) blanket vaccination in a sow herd on productive parameters, PCV-2 infection and immune status ...
Revisiting Porcine Circovirus Disease Diagnostic Criteria in the Current Porcine Circovirus 2 Epidemiological Context
(MDPI, 2022-03-02)
Current knowledge on porcine circovirus diseases (PCVD) caused by Porcine circovirus 2 (PCV-2) includes the subclinical infection (PCV-2-SI), systemic (PCV-2-SD) and reproductive (PCV-2-RD) diseases, ...
Genetic diversification patterns in swine influenza A virus (H1N2) in vaccinated and nonvaccinated animals
(Frontiers Media, 2023-09-15)
Influenza A viruses (IAVs) are characterized by having a segmented genome, low
proofreading polymerases, and a wide host range. Consequently, IAVs are
constantly evolving in nature causing a threat ...
Detection of Porcine Circovirus 3 in Wildlife Species in Spain
(MDPI, 2020-05-01)
Porcine circovirus 3 (PCV-3) is the third member of the family Circoviridae, genus Circovirus, able to infect swine. A high prevalence of viral DNA has been recorded in wild boars. Recently, PCV-3 DNA ...
Enhanced replication fitness of MERS-CoV clade B over clade A strains in camelids explains the dominance of clade B strains in the Arabian Peninsula
(Taylor & Francis Open Access, 2022-02-01)
Middle East respiratory syndrome coronavirus (MERS-CoV) continues infecting humans and dromedary camels. While MERS-CoV strains from the Middle East region are subdivided into two clades (A and B), all ...