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Clinical course impacts early kinetics,magnitude, and amplitude of SARS-CoV-2 neutralizing antibodies beyond 1 year after infection
(Cell Press, 2022-01-24)
To understand the determinants of long-term immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the concurrent impact of vaccination and emerging variants, we follow a ...
The FlagT4G Vaccine Confers a Strong and Regulated Immunity and Early Virological Protection against Classical Swine Fever
(MDPI, 2022-09-02)
Control of classical swine fever virus (CSFV) in endemic countries relies on vaccination, mostly using vaccines that do not allow for differentiation of vaccinated from infected animals (DIVA). FlagT4G ...
Protective Immunity to Listeria Monocytogenes Infection Mediated by Recombinant Listeria innocua Harboring the VGC Locus
(Public Library of Science, 2012-04-19)
In this study we propose a novel bacterial vaccine strategy where non-pathogenic bacteria are complemented with traits
desirable for the induction of protective immunity. To illustrate the proof of ...
Clinical, Pathological and Virological Outcomes of Tissue-Homogenate-Derived and Cell-Adapted Strains of Porcine Epidemic Diarrhea Virus (PEDV) in a Neonatal Pig Model
(MDPI, 2023-12-27)
Porcine epidemic diarrhea virus (PEDV) is characterized by diarrhea, vomiting, dehydration, and high mortality rates in neonatal piglets. Two distinct genogroups, S-INDEL (G1a, G1b) and
non-S INDEL ...
A Novel E2 Glycoprotein Subunit Marker Vaccine Produced in Plant Is Able to Prevent Classical Swine Fever Virus Vertical Transmission after Double Vaccination
(MDPI, 2021-04-22)
The efficacy of a novel subunit vaccine candidate, based in the CSFV E2 glycoprotein
produced in plants to prevent classical swine fever virus (CSFV) vertical transmission, was evaluated.
A Nicotiana ...
The PHH-1V HIPRA vaccine: a new tool in the vaccination strategy against COVID-19
(Sociedad Española de Quimioterapia, 2023-06-12)
Objectives. Vaccination against SARS-CoV-2 is essential
to mitigate the personal, social and global impact of the coronavirus disease (COVID-19) as we move from a pandemic to
an endemic phase. Vaccines ...
Evidence of p75 Neurotrophin Receptor Involvement in the Central Nervous System Pathogenesis of Classical Scrapie in Sheep and a Transgenic Mouse Model
(MDPI, 2021-03-08)
Neurotrophins constitute a group of growth factor that exerts important functions in the nervous system of vertebrates. They act through two classes of transmembrane receptors: tyrosine-kinase receptors ...
A simple method to estimate the number of doses to include in a bank of vaccines. The case of Lumpy Skin Disease in France
(Public Library of Science, 2019-01-25)
A simple method to estimate the size of the vaccine bank needed to control an epidemic of an exotic infectious disease in case of introduction into a country is presented. The method was applied to the ...
Histopathological and virological findings in emaciated pigs from Mexico: an exploratory study
(University of Veterinary and Pharmaceutical Sciences, Brno, 2018-06-27)
The objective of this work was to detect the presence of three main pig respiratory viral agents
(porcine rubulavirus [PorPV], porcine circovirus type 2 [PCV-2], and porcine reproductive and
respiratory ...
ICTV Virus Taxonomy Profile: Asfarviridae
(Microbiology Society, 2018-03-22)
The family Asfarviridae includes the single species African swine fever virus, isolates of which have linear dsDNA genomes of
170–194 kbp. Virions have an internal core, an internal lipid membrane, an ...