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Bottlenecks in the transmission of porcine reproductive and respiratory syndrome virus (PRRSV1) to naïve pigs and the quasi-species variation of the virus during infection in vaccinated pigs
(BMC, 2018-10-19)
This paper describes the results of two experiments regarding porcine reproductive and respiratory syndrome virus (PRRSV1): the first one studied the existence of bottlenecks in an experimental one-to-one ...
Development of pig conventional dendritic cells from bone marrow hematopoietic cells in vitro
(Frontiers Media, 2020-10-08)
In recent years, porcine dendritic cells (DCs) have been identified from pig tissues. However, studying the interaction of porcine DCs with pathogens is still difficult due to the scarcity of DCs in ...
Activation of regulated cell death in the lung of piglets infected with virulent PRRSV-1 Lena strain occurs earlier and mediated by cleaved Caspase-8
(BMC, 2021-01-22)
PRRSV-1 virulent strains cause high fever, marked respiratory disease and severe lesions in lung and lymphoid organs. Regulated cell death (RCD), such as apoptosis, necroptosis and pyroptosis, is triggered ...
Diversity of respiratory viruses present in nasal swabs under influenza suspicion in respiratory disease cases of weaned pigs
(Frontiers Media, 2022-10-19)
Respiratory diseases in weaned pigs are a common problem, with a complex etiology involving both viruses and bacteria. In the present study, we investigated the presence of eleven viruses in nasal swabs, ...
Systemic CD4 cytotoxic T cells improve protection against PRRSV-1 transplacental infection
(Frontiers Media, 2023-01-17)
Background: Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the major swine pathogens causing reproductive failure in sows. Although modified-live virus (MLV) vaccines are available, ...
Interaction of Type 1 Porcine Reproductive and Respiratory Syndrome Virus With In Vitro Derived Conventional Dendritic Cells
(Frontiers Media, 2021-06-02)
The present study delineates the interaction of a typical PRRSV1.1 isolate 3267 (moderate virulence) with in vitro derived pig conventional dendritic cells, cDC1, cDC2, and a CD14+ population (designated ...
Characterization of homologous and heterologous adaptive immune responses in porcine reproductive and respiratory syndrome virus infection
(BMC, 2012-04-19)
The present study characterized the homologous and heterologous immune response in type-I porcine
reproductive and respiratory syndrome virus (PRRSV) infection. Two experiments were conducted: in ...
Cytokine profiles and phenotype regulation of antigen presenting cells by genotype-I porcine reproductive and respiratory syndrome virus isolates
(BMC, 2011-01-18)
The present study examined the immunological response of antigen presenting cells (APC) to genotype-I isolates
of porcine reproductive and respiratory syndrome virus (PRRSV) infection by analysing the ...
Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge
(BioMed Central, 2018-02-15)
Porcine reproductive and respiratory syndrome virus (PRRSv) infection alters the host’s cellular and humoral immune
response. Immunity against PRRSv is multigenic and vary between individuals. The aim ...