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RNA-seq based detection of differentially expressed genes in the skeletal muscle of Duroc pigs with distinct lipid profiles
(Nature Research, 2017-02-14)
We have used a RNA-seq approach to investigate differential expression in the skeletal muscle of swine
(N=52) with divergent lipid profiles i.e. HIGH (increased intramuscular fat and muscle saturated ...
kernInt: A Kernel Framework for Integrating Supervised and Unsupervised Analyses in Spatio-Temporal Metagenomic Datasets
(Frontiers Media, 2021-01-28)
The advent of next-generation sequencing technologies allowed relative quantification of microbiome communities and their spatial and temporal variation. In recent years, supervised learning (i.e., ...
A systems biology framework integrating GWAS and RNA-seq to shed light on the molecular basis of sperm quality in swine
(BMC, 2020-12-08)
Background
Genetic pressure in animal breeding is sparking the interest of breeders for selecting elite boars with higher sperm quality to optimize ejaculate doses and fertility rates. However, the ...
Leveraging host-genetics and gut microbiota to determine immunocompetence in pigs
(BMC, 2021-10-24)
Background: The gut microbiota infuences host performance playing a relevant role in homeostasis and function of
the immune system. The aim of the present work was to identify microbial signatures ...
Expression analysis of candidate genes for fatty acid composition in adipose tissue and identifcation of regulatory regions
(Nature Research, 2018-02-01)
The aim of this work was to study the genetic basis of the backfat expression of lipid-related genes
associated with meat quality traits in pigs. We performed a genome-wide association study with ...
Copy Number Variation on ABCC2-DNMBP Loci Affects the Diversity and Composition of the Fecal Microbiota in Pigs
(American Society for Microbiology, 2023-05-31)
Genetic variation in the pig genome partially modulates the composition of porcine gut microbial communities. Previous studies have been focused on the association between single nucleotide polymorphisms ...
Interrelation between gut microbiota, SCFA, and fatty acid composition in pigs
(American Society for Microbiology, 2023-12-14)
The gut microbiota is a key player in the host metabolism. Some bacteria are able to ferment non-digestible compounds and produce short-chain fatty acids that the host can later transform and accumulate ...
Identification of eQTLs associated with lipid metabolism in Longissimus dorsi muscle of pigs with different genetic backgrounds
(Nature Research, 2020-06-17)
Intramuscular fat content and its fatty acid composition affect porcine meat quality and its nutritional value. The present work aimed to identify genomic variants regulating the expression in the porcine ...
Comparing the mRNA expression profile and the genetic determinism of intramuscular fat traits in the porcine gluteus medius and longissimus dorsi muscles
(BMC, 2019-03-04)
Background
Intramuscular fat (IMF) content and composition have a strong impact on the nutritional and organoleptic properties of porcine meat. The goal of the current work was to compare the patterns ...
Identification of strong candidate genes for backfat and intramuscular fatty acid composition in three crosses based on the Iberian pig
(Nature Research, 2020-08-18)
Meat quality has an important genetic component and can be modified by the fatty acid (FA) composition and the amount of fat contained in adipose tissue and muscle. The present study aimed to find genomic ...